Wall and Melzack's Textbook of Pain, 5e

Cover......Page 1
ISBN:    9780443072871......Page 2
Copyright......Page 3
Contributors......Page 8
Foreword......Page 12
Preface......Page 14
Dedication......Page 15
Abbreviations and Acronyms......Page 16
Peripheral mechanisms of cutaneous nociception......Page 22
Cellular and molecular properties of primary afferent neurons......Page 54
Inflammatory mediators and modulators of pain......Page 68
Neuroanatomical substrates of spinal nociception......Page 92
Plasticity and pain: role of the dorsal horn......Page 110
Representation of pain in the brain......Page 126
Central nervous system mechanisms of pain modulation......Page 144
Development of pain pathways and mechanisms......Page 162
The genetics of pain......Page 178
Animal models of pain......Page 194
Autonomic-endocri ne-immune interact ions in acute and chronic pain......Page 224
Itch......Page 238
Emotions and psychobiology......Page 250
Cognitive and learning aspects......Page 260
Psychiatric disorders and pain......Page 278
Studies of pain in human subjects......Page 286
Pain assessment in adult patients......Page 310
Measurement and assessment of paediatric pain......Page 324
Assessment of pain beliefs, coping and function......Page 336
Hypnotic analgesia......Page 348
The cognitive-behavioural approach to pain management......Page 358
Pain, opiates and addiction......Page 368
Placebo analgesia......Page 380
Central pharmacology of nociceptive transmission......Page 390
Methods of therapeutic trials......Page 434
Opiates: basic mechanisms......Page 446
Opioids: clinical use......Page 462
Antipyretic analgesics: basic aspects......Page 478
NSAIDS and Coxibs: clinical use......Page 490
Antidepressant analgesics: a systematic review and comparative study......Page 500
Anticonvulsant medications in neuropathic pain......Page 518
Local anaesthetic blocks and epidurals......Page 526
Cannabinoids......Page 540
Analgesic drugs in development......Page 560
Supratentorial neurosurgery for the treatment of pain......Page 572
Spinal cord and brain stimulation......Page 582
Transcutaneous electrical nerve stimulation and acupuncture......Page 602
Peripheral and central nervous system surgery for pain......Page 610
Physiotherapy and pain......Page 622
Basic mechanisms of deep somatic pain......Page 640
Postoperative pain and its management......Page 654
Osteoarthritis and rheumatoid arthritis......Page 672
Myofascial pain and fibromyalgia syndrome......Page 688
Surgical treatment for back and neck pain......Page 702
Low back pain......Page 718
Repetitive strain injury......Page 728
Visceral pain: basic mechanisms......Page 740
Thorax......Page 756
A clinical perspective on abdominal pain......Page 772
Genitourinary pain......Page 796
Obstetric pain......Page 812
Acute and chronic dental and orofacial pain......Page 838
Headache......Page 856
Primary neurovascular headache......Page 870
Tension-type headache......Page 894
Pain in and around the eye......Page 906
Response of nerves to injury in relation to neuropathic pain......Page 924
Mechanisms of experimental neuropathic pain: integration from animal models......Page 948
Central consequences of peripheral nerve damage......Page 966
Phantom limb......Page 980
PainfuI peripheral neuropathies......Page 992
Trigeminal and glossop haryngeal neuralgia......Page 1020
Complex regional pain syndromes......Page 1030
Root disorders and arachnoiditis......Page 1048
Pain following spinal cord injury......Page 1062
Central pain......Page 1076
Pharmacological therapy for neuropathic pain......Page 1094
Cancer pain: causes, consequences and therapeutic opportunities......Page 1106
The assessment of cancer pain......Page 1118
Analgesic therapy and palliative care in children......Page 1146
Cancer pain: treatment overview......Page 1160
Pain control in the care of the dying......Page 1178
Pain in the elderly......Page 1188
Sex and gender differences in pain and its relief......Page 1200
Epidemiology of pain......Page 1218
Index......Page 1234